Bicarbonate Ion → 2-{2-[4-((5-Fluoro-3-indolyl)methyl)piperidino]ethyl}-3-phenyl-1,2-benzisothiazole 1,1-dioxide
Reaction equation
[C:38](=[O:39])([OH:40])[O-:41].[CH3:43][N:44]([CH3:45])[CH:46]=[O:47].[Cl:1][CH2:2][CH2:3][N:4]1[S:5](=[O:19])(=[O:20])[c:6]2[c:7]([cH:15][cH:16][cH:17][cH:18]2)[CH:8]1[c:9]1[cH:10][cH:11][cH:12][cH:13][cH:14]1.[F:21][c:22]1[cH:23][c:24]2[c:25]([CH2:31][CH:32]3[CH2:33][CH2:34][NH:35][CH2:36][CH2:37]3)[cH:26][nH:27][c:28]2[cH:29][cH:30]1.[Na+:42].[O:48]1[CH2:49][CH2:50][CH2:51][CH2:52]1>>[CH2:2]([CH2:3][N:4]1[S:5](=[O:19])(=[O:20])[c:6]2[c:7]([cH:15][cH:16][cH:17][cH:18]2)[CH:8]1[c:9]1[cH:10][cH:11][cH:12][cH:13][cH:14]1)[N:35]1[CH2:34][CH2:33][CH:32]([CH2:31][c:25]2[c:24]3[cH:23][c:22]([F:21])[cH:30][cH:29][c:28]3[nH:27][cH:26]2)[CH2:37][CH2:36]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-201423835cde4c0b8283d3f1a5257923
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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