Water → tert-Butyl 4-(isoquinolin-1-yl)piperazine-1-carboxylate
Reaction equation
[C:12]([CH3:13])([CH3:14])([CH3:15])[O:16][C:17](=[O:18])[N:19]1[CH2:20][CH2:21][NH:22][CH2:23][CH2:24]1.[CH2:25]1[CH2:26][CH2:27][C:28]2=[N:33][CH2:32][CH2:31][CH2:30][N:29]2[CH2:34][CH2:35]1.[CH3:36][C:37]([O:38][I:39]1([O:49][C:50]([CH3:51])=[O:52])([O:53][C:54]([CH3:55])=[O:56])[c:40]2[c:41]([cH:42][cH:43][cH:44][cH:45]2)[C:46](=[O:47])[O:48]1)=[O:57].[Cl:1][c:2]1[n:3][cH:4][cH:5][c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]12.[OH2:58]>>[c:2]1([N:22]2[CH2:21][CH2:20][N:19]([C:17]([O:16][C:12]([CH3:13])([CH3:14])[CH3:15])=[O:18])[CH2:24][CH2:23]2)[n:3][cH:4][cH:5][c:6]2[cH:7][cH:8][cH:9][cH:10][c:11]12Participants
6
Sources & evidence
- ORD record
- ord-df4fd73485c249c389ae9df76b10492b
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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