Chloride → 1-(4-Chlorobenzyl)-7-cyclohexyl-3-hydroxy-3-methyl-1,7-diazaspiro[4.4]nonan-6-one
Reaction equation
[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[CH3:2][C:3](=[CH2:4])[CH2:5][Mg+:6].[Cl-:1].[Cl:7][c:8]1[cH:9][cH:10][c:11]([CH2:12][N:13]2[CH2:14][C:15](=[O:29])[CH2:16][C:17]23[C:18](=[O:28])[N:19]([CH:22]2[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27]2)[CH2:20][CH2:21]3)[cH:30][cH:31]1>>[CH3:2][C:15]1([OH:29])[CH2:14][N:13]([CH2:12][c:11]2[cH:10][cH:9][c:8]([Cl:7])[cH:31][cH:30]2)[C:17]2([CH2:16]1)[C:18](=[O:28])[N:19]([CH:22]1[CH2:23][CH2:24][CH2:25][CH2:26][CH2:27]1)[CH2:20][CH2:21]2Participants
5
Sources & evidence
- ORD record
- ord-205c9db89953466f973b130dc87bb280
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
Loading…