Methane → Ethyl 5-amino-7-fluoro-1-(2-fluorocyclopropyl)-8-methyl-4-oxoquinoline-3-carboxylate
Reaction equation
[C:35].[CH3:26][CH2:27][CH2:28][CH2:29][CH2:30][CH3:31].[CH3:32][C:33]#[N:34].[CH3:37][CH2:38][O:39][C:40](=[O:41])[CH3:42].[F:1][c:2]1[cH:3][c:4]([N+:23]([O-:24])=[O:25])[c:5]2[c:6](=[O:22])[c:7]([C:17](=[O:18])[O:19][CH2:20][CH3:21])[cH:8][n:9]([CH:13]3[CH:14]([F:16])[CH2:15]3)[c:10]2[c:11]1[CH3:12].[Pd:36]>>[F:1][c:2]1[cH:3][c:4]([NH2:23])[c:5]2[c:6](=[O:22])[c:7]([C:17](=[O:18])[O:19][CH2:20][CH3:21])[cH:8][n:9]([CH:13]3[CH:14]([F:16])[CH2:15]3)[c:10]2[c:11]1[CH3:12]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-cc84e9f271c54e708efee664a560501e
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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