Water → 5-Chloro-2-(4-fluoro-phenoxy)-N-[4-(1-hydroxy-1-methyl-ethyl)-benzyl]-nicotinamide
Reaction equation
[CH3:19][N:20]1[CH2:21][CH2:22][O:23][CH2:24][CH2:25]1.[Cl:1][c:2]1[cH:3][n:4][c:5]([O:11][c:12]2[cH:13][cH:14][c:15]([F:18])[cH:16][cH:17]2)[c:6]([C:7](=[O:8])[OH:9])[cH:10]1.[Cl:26][C:27]([O:28][CH2:29][CH:30]([CH3:31])[CH3:32])=[O:33].[Cl:46][CH2:47][Cl:48].[OH2:49].[OH:34][C:35]([CH3:36])([CH3:37])[c:38]1[cH:39][cH:40][c:41]([CH2:42][NH2:43])[cH:44][cH:45]1>>[Cl:1][c:2]1[cH:3][n:4][c:5]([O:11][c:12]2[cH:13][cH:14][c:15]([F:18])[cH:16][cH:17]2)[c:6]([C:7](=[O:9])[NH:43][CH2:42][c:41]2[cH:40][cH:39][c:38]([C:35]([OH:34])([CH3:36])[CH3:37])[cH:45][cH:44]2)[cH:10]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-5e9c23dd763e41c2913a94ca169204b3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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