Tetrahydrofuran → [6-(3-Methoxyphenyl)-2-(morpholin-4-ylethyl)pyrimidin-4-yl]-3-pyridylamine

HRID 1141145Notes

Reaction equation

HRID 1141145 reaction equation
[Al+3:2].[CH2:37]1[O:38][CH2:39][CH2:40][CH2:41]1.[CH3:7][O:8][c:9]1[cH:10][c:11](-[c:15]2[cH:16][c:17]([NH:30][c:31]3[cH:32][n:33][cH:34][cH:35][cH:36]3)[n:18][c:19]([CH2:21][C:22](=[O:23])[N:24]3[CH2:25][CH2:26][O:27][CH2:28][CH2:29]3)[n:20]2)[cH:12][cH:13][cH:14]1.[H-:1].[H-:4].[H-:5].[H-:6].[Li+:3]>>[CH3:7][O:8][c:9]1[cH:10][c:11](-[c:15]2[cH:16][c:17]([NH:30][c:31]3[cH:32][n:33][cH:34][cH:35][cH:36]3)[n:18][c:19]([CH2:21][CH2:22][N:24]3[CH2:25][CH2:26][O:27][CH2:28][CH2:29]3)[n:20]2)[cH:12][cH:13][cH:14]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 597896702-[6-(3-Methoxyphenyl)-4-(3-pyridylamino)pyrimidin-2-yl]-1-morpholin-4-ylethan-1-one

Product 1

HCID 59789786[6-(3-Methoxyphenyl)-2-(morpholin-4-ylethyl)pyrimidin-4-yl]-3-pyridylamine

Sources & evidence

ORD record
ord-3f38b652fd13437ba79e4bb680cb789d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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