Water → N-cyclopropyl-4-methyl-3-(7-(3-oxopiperazin-1-yl)thieno[2,3-d]pyridazin-2-yl)benzamide
Reaction equation
[CH3:40][N:41]1[CH2:42][CH2:43][CH2:44][C:45]1=[O:46].[CH:31]([N:32]([CH2:33][CH3:34])[CH:35]([CH3:36])[CH3:37])([CH3:38])[CH3:39].[Cl:1][c:2]1[n:3][n:4][cH:5][c:6]2[c:7]1[s:8][c:9](-[c:11]1[cH:12][c:13]([C:14](=[O:15])[NH:16][CH:17]3[CH2:18][CH2:19]3)[cH:20][cH:21][c:22]1[CH3:23])[cH:10]2.[NH:24]1[C:25](=[O:30])[CH2:26][NH:27][CH2:28][CH2:29]1.[OH2:47]>>[c:2]1([N:27]2[CH2:26][C:25](=[O:30])[NH:24][CH2:29][CH2:28]2)[n:3][n:4][cH:5][c:6]2[c:7]1[s:8][c:9](-[c:11]1[cH:12][c:13]([C:14](=[O:15])[NH:16][CH:17]3[CH2:18][CH2:19]3)[cH:20][cH:21][c:22]1[CH3:23])[cH:10]2Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-2619a05d808e4530a2c1a349d6fe770c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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