Tetrahydrofuran → N-heptyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]-1H-indole-5-carboxamide

HRID 1141920Notes

Reaction equation

HRID 1141920 reaction equation
[CH2:29]([CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH3:35])[NH2:36].[CH2:43]1[O:44][CH2:45][CH2:46][CH2:47]1.[CH3:37][CH2:38][O:39][C:40]([CH3:41])=[O:42].[O:1]1[CH2:2][CH2:3][CH:4]([CH2:7][n:8]2[cH:9][c:10]([C:20](=[O:21])[CH:22]3[C:23]([CH3:27])([CH3:28])[C:24]3([CH3:25])[CH3:26])[c:11]3[cH:12][c:13]([C:17](=[O:18])[OH:19])[cH:14][cH:15][c:16]23)[CH2:5][CH2:6]1>>[O:1]1[CH2:2][CH2:3][CH:4]([CH2:7][n:8]2[cH:9][c:10]([C:20](=[O:21])[CH:22]3[C:23]([CH3:27])([CH3:28])[C:24]3([CH3:25])[CH3:26])[c:11]3[cH:12][c:13]([C:17](=[O:19])[NH:36][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH3:35])[cH:14][cH:15][c:16]23)[CH2:5][CH2:6]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 81271-HeptanamineHCID 8857Ethyl AcetateHCID 67269817HCID 67269817, compound

Product 1

HCID 67270213N-heptyl-1-(tetrahydro-2H-pyran-4-ylmethyl)-3-[(2,2,3,3-tetramethylcyclopropyl)carbonyl]-1H-indole-5-carboxamide

Sources & evidence

ORD record
ord-f16ad279534549dc8c2cb9a1ba7c0a13
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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