Water → 4-[2-(4-Fluoro-phenylamino)-imidazo[2,1-b][1,3,4]thiadiazol-5-yl]-phenol
Reaction equation
[C:28](=[O:29])([O-:30])[O-:31].[CH2:35]1[O:36][CH2:37][CH2:38][O:39][CH2:40]1.[Cl:41][CH2:42][Cl:43].[Cs+:32].[Cs+:33].[F:1][c:2]1[cH:3][cH:4][c:5]([NH:8][c:9]2[n:10][n:11]3[c:12]([s:13]2)[n:14][cH:15][c:16]3[I:17])[cH:6][cH:7]1.[OH2:34].[OH:18][c:19]1[cH:20][cH:21][c:22]([B:25]([OH:26])[OH:27])[cH:23][cH:24]1.[Pd:44].[c:102]1([P:103]([c:104]2[cH:105][cH:106][cH:107][cH:108][cH:109]2)[c:110]2[cH:111][cH:112][cH:113][cH:114][cH:115]2)[cH:116][cH:117][cH:118][cH:119][cH:120]1.[c:45]1([P:46]([c:47]2[cH:48][cH:49][cH:50][cH:51][cH:52]2)[c:53]2[cH:54][cH:55][cH:56][cH:57][cH:58]2)[cH:59][cH:60][cH:61][cH:62][cH:63]1.[c:64]1([P:65]([c:66]2[cH:67][cH:68][cH:69][cH:70][cH:71]2)[c:72]2[cH:73][cH:74][cH:75][cH:76][cH:77]2)[cH:78][cH:79][cH:80][cH:81][cH:82]1.[c:83]1([P:84]([c:85]2[cH:86][cH:87][cH:88][cH:89][cH:90]2)[c:91]2[cH:92][cH:93][cH:94][cH:95][cH:96]2)[cH:97][cH:98][cH:99][cH:100][cH:101]1>>[F:1][c:2]1[cH:3][cH:4][c:5]([NH:8][c:9]2[n:10][n:11]3[c:12]([s:13]2)[n:14][cH:15][c:16]3-[c:22]2[cH:21][cH:20][c:19]([OH:18])[cH:24][cH:23]2)[cH:6][cH:7]1Participants
10
Reactant 9
Product 1
Sources & evidence
- ORD record
- ord-4abdd327c073435ca270fd078b09345d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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