Water → Methyl 2-(4-hydroxypiperidin-1-yl)acetate

HRID 1142189Notes

Reaction equation

HRID 1142189 reaction equation
[Br:8][CH2:9][C:10](=[O:11])[O:12][CH3:13].[Cl:15][CH2:16][Cl:17].[OH2:14].[OH:1][CH:2]1[CH2:3][CH2:4][NH:5][CH2:6][CH2:7]1>>[OH:1][CH:2]1[CH2:3][CH2:4][N:5]([CH2:9][C:10](=[O:11])[O:12][CH3:13])[CH2:6][CH2:7]1

Participants

5

Reactant 4

HCID 962WaterHCID 6344DichloromethaneHCID 60984Methyl bromoacetateHCID 79341Piperidin-4-ol

Product 1

HCID 28837753Methyl 2-(4-hydroxypiperidin-1-yl)acetate

Sources & evidence

ORD record
ord-6a5c7f2337e34cb3933942bc778f7bf5
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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