Hydrochloric Acid → 9-(Pyridin-4-yl-methyl)-3,9-diazaspiro[5.5]undecane-3-carboxylic acid tert-butyl ester
Reaction equation
[Br:21][CH2:22][c:23]1[cH:24][cH:25][n:26][cH:27][cH:28]1.[C:3]([CH3:4])([CH3:5])([CH3:6])[O:7][C:8](=[O:9])[N:10]1[CH2:11][CH2:12][C:13]2([CH2:14][CH2:15]1)[CH2:16][CH2:17][NH:18][CH2:19][CH2:20]2.[ClH:29].[H-:2].[Na+:1].[O:30]=[CH:31][N:32]([CH3:33])[CH3:34]>>[C:3]([CH3:4])([CH3:5])([CH3:6])[O:7][C:8](=[O:9])[N:10]1[CH2:11][CH2:12][C:13]2([CH2:14][CH2:15]1)[CH2:16][CH2:17][N:18]([CH2:22][c:23]1[cH:24][cH:25][n:26][cH:27][cH:28]1)[CH2:19][CH2:20]2Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-a268ae4d198c499889ce39e7294af92c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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