Acetic Acid → 2-[3-(1-Piperidinylmethyl)-2-pyridinyl]-1H-isoindole-1,3(2H)-dione
Reaction equation
[Br:1][CH:2]([c:3]1[c:4]([N:9]2[C:10](=[O:19])[c:11]3[c:12]([cH:15][cH:16][cH:17][cH:18]3)[C:13]2=[O:14])[n:5][cH:6][cH:7][cH:8]1)[Br:20].[C:27]([OH:28])(=[O:29])[CH3:30].[CH2:21]1[CH2:22][CH2:23][NH:24][CH2:25][CH2:26]1.[CH3:40][CH2:41][O:42][C:43]([CH3:44])=[O:45].[Cl:37][CH2:38][Cl:39].[K+:31].[K+:32].[O-:33][C:34]([O-:35])=[O:36]>>[CH2:2]([c:3]1[c:4]([N:9]2[C:10](=[O:19])[c:11]3[c:12]([cH:15][cH:16][cH:17][cH:18]3)[C:13]2=[O:14])[n:5][cH:6][cH:7][cH:8]1)[N:24]1[CH2:23][CH2:22][CH2:21][CH2:26][CH2:25]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-bd0416d01d1e4917957e50526f93f3d0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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