Tetrahydrofuran → N-(2-bromo-4-(1-methylethyl)phenyl)-N-ethyl-4-acetyl-6-methylpyrimidinamine
Reaction equation
[Br:1][c:2]1[c:3]([N:11]([c:12]2[n:13][c:14]([CH3:21])[cH:15][c:16]([C:18](=[O:19])[OH:20])[n:17]2)[CH2:22][CH3:23])[cH:4][cH:5][c:6]([CH:8]([CH3:9])[CH3:10])[cH:7]1.[CH2:32]1[O:33][CH2:34][CH2:35][CH2:36]1.[CH3:24][Li:25].[CH3:26][CH2:27][O:28][C:29](=[O:30])[CH3:31]>>[Br:1][c:2]1[c:3]([N:11]([c:12]2[n:13][c:14]([CH3:21])[cH:15][c:16]([C:18](=[O:20])[CH3:26])[n:17]2)[CH2:22][CH3:23])[cH:4][cH:5][c:6]([CH:8]([CH3:9])[CH3:10])[cH:7]1Participants
5
Sources & evidence
- ORD record
- ord-39f836a4b6af4d57b437f42e79baeab5
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
Loading…