Sodium ion → 3-(4-Iodophenoxy)-1-azabicyclo[2.2.2]octane

HRID 1143980Notes

Reaction equation

HRID 1143980 reaction equation
[N:20]12[CH2:21][CH:22]([OH:28])[CH:23]([CH2:24][CH2:25]1)[CH2:26][CH2:27]2.[Na+:38].[O:39]1[CH2:40][CH2:41][O:42][CH2:43][CH2:44]1.[OH-:37].[OH:29][c:30]1[cH:31][cH:32][c:33]([I:34])[cH:35][cH:36]1.[c:1]1([P:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[N:20]12[CH2:21][CH:22]([O:28][c:30]3[cH:31][cH:32][c:33]([I:34])[cH:35][cH:36]3)[CH:23]([CH2:24][CH2:25]1)[CH2:26][CH2:27]2

Participants

7

Reactant 6

HCID 923Sodium ionHCID 961HydroxideHCID 108944-IodophenolHCID 11776TriphenylphosphineHCID 15381(+-)-3-QuinuclidinolHCID 312751,4-Dioxane

Product 1

HCID 210726043-(4-Iodophenoxy)-1-azabicyclo[2.2.2]octane

Sources & evidence

ORD record
ord-690268a51b6049309f2df7294ed71824
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…