Acetic Acid → Tert-butyl (2-{4-[4-(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)thiazol-2-yl]piperidin-1-yl}ethyl)carbamate
Reaction equation
[BrH:6].[C:43]([O:44][BH-:45]([O:46][C:47](=[O:48])[CH3:49])[O:50][C:51](=[O:52])[CH3:53])(=[O:54])[CH3:55].[CH2:1]1[O:2][CH2:3][CH2:4][CH2:5]1.[CH3:57][C:58](=[O:59])[OH:60].[CH3:7][C:8]1([CH3:31])[c:9]2[cH:10][cH:11][c:12](-[c:20]3[n:21][c:22]([CH:25]4[CH2:26][CH2:27][NH:28][CH2:29][CH2:30]4)[s:23][cH:24]3)[cH:13][c:14]2[C:15]([CH3:18])([CH3:19])[CH2:16][CH2:17]1.[Na+:56].[O:32]=[CH:33][CH2:34][NH:35][C:36]([O:37][C:38]([CH3:39])([CH3:40])[CH3:41])=[O:42]>>[CH3:7][C:8]1([CH3:31])[c:9]2[cH:10][cH:11][c:12](-[c:20]3[n:21][c:22]([CH:25]4[CH2:26][CH2:27][N:28]([CH2:33][CH2:34][NH:35][C:36]([O:37][C:38]([CH3:39])([CH3:40])[CH3:41])=[O:42])[CH2:29][CH2:30]4)[s:23][cH:24]3)[cH:13][c:14]2[C:15]([CH3:18])([CH3:19])[CH2:16][CH2:17]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-c4608233bdc64cc1822966531f926f60
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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