Water → Trimethyl(2,3,2'-trifluoro-4'-iodobiphenyl-4-yl)silane

HRID 1144349Notes

Reaction equation

HRID 1144349 reaction equation
[Br:6][c:7]1[cH:8][c:9]([F:25])[c:10](-[c:13]2[c:14]([F:24])[c:15]([F:23])[c:16]([Si:19]([CH3:20])([CH3:21])[CH3:22])[cH:17][cH:18]2)[cH:11][cH:12]1.[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[CH3:1][CH2:2][CH2:3][CH2:4][Li:5].[CH3:36][O:37][C:38]([CH3:39])([CH3:40])[CH3:41].[I:26][CH2:27][CH2:28][I:29].[OH2:30]>>[c:7]1([I:26])[cH:8][c:9]([F:25])[c:10](-[c:13]2[c:14]([F:24])[c:15]([F:23])[c:16]([Si:19]([CH3:20])([CH3:21])[CH3:22])[cH:17][cH:18]2)[cH:11][cH:12]1

Participants

7

Reactant 6

HCID 962WaterHCID 8028TetrahydrofuranHCID 122241,2-DiiodoethaneHCID 15413tert-Butyl methyl etherHCID 11462508(4'-Bromo-2,3,2'-trifluorobiphenyl-4-yl)trimethylsilaneHCID 178418339Butyllithium

Product 1

HCID 11304300Trimethyl(2,3,2'-trifluoro-4'-iodobiphenyl-4-yl)silane

Sources & evidence

ORD record
ord-d9084e8306644eff8dbfafe9e2ee1a0f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…