Hydrochloric Acid → Ethyl 7-(4-acetyl-1-piperazinyl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylate
Reaction equation
[C:2]([CH3:3])(=[O:4])[N:5]1[CH2:6][CH2:7][NH:8][CH2:9][CH2:10]1.[CH2:67]([Cl:68])[Cl:69].[CH3:11][CH2:12][N:13]([CH2:14][CH3:15])[CH2:16][CH3:17].[CH3:62][CH2:63][O:64][CH2:65][CH3:66].[ClH:1].[F:18][c:19]1[c:20](-[n:26]2[cH:27][c:28]([C:57](=[O:58])[O:59][CH2:60][CH3:61])[c:29](=[O:56])[c:30]3[cH:31][c:32]([F:55])[c:33]([O:36][S:37]([c:38]4[c:39]([CH:40]([CH3:41])[CH3:42])[cH:43][c:44]([CH:45]([CH3:46])[CH3:47])[cH:48][c:49]4[CH:50]([CH3:51])[CH3:52])(=[O:53])=[O:54])[n:34][c:35]23)[cH:21][cH:22][c:23]([F:25])[cH:24]1>>[C:2]([CH3:3])(=[O:4])[N:5]1[CH2:6][CH2:7][N:8]([c:33]2[c:32]([F:55])[cH:31][c:30]3[c:29](=[O:56])[c:28]([C:57](=[O:58])[O:59][CH2:60][CH3:61])[cH:27][n:26](-[c:20]4[c:19]([F:18])[cH:24][c:23]([F:25])[cH:22][cH:21]4)[c:35]3[n:34]2)[CH2:9][CH2:10]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-beed37cdfa624bd7b6a10bd48fefffbb
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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