Hydrochloric Acid → N-(4-(4-(3-Cyclopropyl-3-fluoroazetidin-1-yl)-6-(pyridin-2-ylamino)pyrimidin-2-ylthio)phenyl)-3,3,3-trifluoropropanamide
Reaction equation
[CH2:48]1[O:49][CH2:50][CH2:51][O:52][CH2:53]1.[CH:31]1([C:34]2([F:38])[CH2:35][NH:36][CH2:37]2)[CH2:32][CH2:33]1.[CH:39]([N:40]([CH2:41][CH3:42])[CH:43]([CH3:44])[CH3:45])([CH3:46])[CH3:47].[Cl:1][c:2]1[n:3][c:4]([S:15][c:16]2[cH:17][cH:18][c:19]([NH:22][C:23]([CH2:24][C:25]([F:26])([F:27])[F:28])=[O:29])[cH:20][cH:21]2)[n:5][c:6]([NH:8][c:9]2[n:10][cH:11][cH:12][cH:13][cH:14]2)[cH:7]1.[ClH:30]>>[c:2]1([N:36]2[CH2:35][C:34]([CH:31]3[CH2:32][CH2:33]3)([F:38])[CH2:37]2)[n:3][c:4]([S:15][c:16]2[cH:17][cH:18][c:19]([NH:22][C:23]([CH2:24][C:25]([F:26])([F:27])[F:28])=[O:29])[cH:20][cH:21]2)[n:5][c:6]([NH:8][c:9]2[n:10][cH:11][cH:12][cH:13][cH:14]2)[cH:7]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-ad5acff166864f65a40f22be9266b2b0
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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