Dichloromethane → 1H-Pyrrolo[2,3-b]pyridine, 3-(cyclopropylmethyl)-1-(phenylsulfonyl)-

HRID 1144962Notes

Reaction equation

HRID 1144962 reaction equation
[CH2:24]([SiH:25]([CH2:26][CH3:27])[CH2:28][CH3:29])[CH3:30].[CH:1]1([CH:4]([OH:5])[c:6]2[cH:7][n:8]([S:15](=[O:16])(=[O:17])[c:18]3[cH:19][cH:20][cH:21][cH:22][cH:23]3)[c:9]3[n:10][cH:11][cH:12][cH:13][c:14]23)[CH2:2][CH2:3]1.[Cl:38][CH2:39][Cl:40].[F:31][C:32]([F:33])([F:34])[C:35]([OH:36])=[O:37]>>[CH:1]1([CH2:4][c:6]2[cH:7][n:8]([S:15](=[O:16])(=[O:17])[c:18]3[cH:19][cH:20][cH:21][cH:22][cH:23]3)[c:9]3[n:10][cH:11][cH:12][cH:13][c:14]23)[CH2:2][CH2:3]1

Participants

5

Reactant 4

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 12052TriethylsilaneHCID 671557641H-Pyrrolo[2,3-b]pyridine-3-methanol, a-cyclopropyl-1-(phenylsulfonyl)-

Product 1

HCID 671558421H-Pyrrolo[2,3-b]pyridine, 3-(cyclopropylmethyl)-1-(phenylsulfonyl)-

Sources & evidence

ORD record
ord-d24044eea3394a57a9308aea5a65c0b1
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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