Tetrahydrofuran → 3-Bromo-pyrrolidine-1-carboxylic acid tert-butyl ester
Reaction equation
[Br:33][C:34]([Br:35])([Br:36])[Br:37].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([OH:13])[CH2:11][CH2:12]1.[CH2:38]1[O:39][CH2:40][CH2:41][CH2:42]1.[c:14]1([P:15]([c:16]2[cH:17][cH:18][cH:19][cH:20][cH:21]2)[c:22]2[cH:23][cH:24][cH:25][cH:26][cH:27]2)[cH:28][cH:29][cH:30][cH:31][cH:32]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([Br:33])[CH2:11][CH2:12]1Participants
5
Sources & evidence
- ORD record
- ord-dd30543c8520414982b280ee043f1d40
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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