Tetrahydrofuran → [4,4-Difluoro-1-[4-nitro-3-(trifluoromethyl)phenyl]pyrrolidin-2-yl]methanol
Reaction equation
[CH2:25]1[O:26][CH2:27][CH2:28][CH2:29]1.[CH3:30][CH2:31][O:32][C:33](=[O:34])[CH3:35].[F:1][C:2]1([F:24])[CH2:3][CH:4]([C:20](=[O:21])[O:22][CH3:23])[N:5]([c:7]2[cH:8][c:9]([C:16]([F:17])([F:18])[F:19])[c:10]([N+:13](=[O:14])[O-:15])[cH:11][cH:12]2)[CH2:6]1>>[F:1][C:2]1([F:24])[CH2:3][CH:4]([CH2:20][OH:21])[N:5]([c:7]2[cH:8][c:9]([C:16]([F:17])([F:18])[F:19])[c:10]([N+:13](=[O:14])[O-:15])[cH:11][cH:12]2)[CH2:6]1Participants
4
Sources & evidence
- ORD record
- ord-376375b7bb1f4aae8e2c183d88f39141
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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