Tetrahydrofuran → (1-Benzyl-3-trifluoromethyl-pyrrolidin-3-YL)-methanol
Reaction equation
[Al+3:21].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][C:10]([C:13](=[O:14])[OH:15])([C:16]([F:17])([F:18])[F:19])[CH2:11][CH2:12]1.[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[H-:20].[H-:23].[H-:24].[H-:25].[Li+:22]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][C:10]([CH2:13][OH:14])([C:16]([F:17])([F:18])[F:19])[CH2:11][CH2:12]1Participants
6
Sources & evidence
- ORD record
- ord-63bb3537fa304a53b778c53fbcaf8d2d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
Loading…