Tetrahydrofuran → N-[4-chloro-2-(hydroxy-pyridin-3-yl-methyl)-phenyl]-2,2-dimethyl-propionamide
Reaction equation
[CH2:34]1[O:35][CH2:36][CH2:37][CH2:38]1.[CH3:15][CH2:16][CH2:17][CH2:18][Li:19].[CH3:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25].[Cl:1][c:2]1[cH:3][cH:4][c:5]([NH:8][C:9]([C:10]([CH3:11])([CH3:12])[CH3:13])=[O:14])[cH:6][cH:7]1.[n:26]1[cH:27][c:28]([CH:32]=[O:33])[cH:29][cH:30][cH:31]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]([NH:8][C:9]([C:10]([CH3:11])([CH3:12])[CH3:13])=[O:14])[c:6]([CH:32]([c:28]2[cH:27][n:26][cH:31][cH:30][cH:29]2)[OH:33])[cH:7]1Participants
6
Sources & evidence
- ORD record
- ord-ccc8d18bf0a0472c9158e9af142e9d34
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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