Hydrochloric Acid → 6-methoxy-4-[(2-methyl-1H-indol-5-yl)oxy]-7-[2-(tetrahydro-5H-[1,3]dioxolo[4,5-c]pyrrol-5-yl)ethoxy]quinazoline
Reaction equation
[C:37](=[O:38])([O-:39])[O-:40].[Cl:1][CH2:2][CH2:3][O:4][c:5]1[c:6]([O:26][CH3:27])[cH:7][c:8]2[c:9]([O:15][c:16]3[cH:17][c:18]4[cH:19][c:20]([CH3:25])[nH:21][c:22]4[cH:23][cH:24]3)[n:10][cH:11][n:12][c:13]2[cH:14]1.[ClH:28].[I-:44].[K+:41].[K+:42].[K+:43].[O:29]1[CH2:30][O:31][CH:32]2[CH:33]1[CH2:34][NH:35][CH2:36]2.[O:45]=[CH:46][N:47]([CH3:48])[CH3:49]>>[CH2:2]([CH2:3][O:4][c:5]1[c:6]([O:26][CH3:27])[cH:7][c:8]2[c:9]([O:15][c:16]3[cH:17][c:18]4[cH:19][c:20]([CH3:25])[nH:21][c:22]4[cH:23][cH:24]3)[n:10][cH:11][n:12][c:13]2[cH:14]1)[N:35]1[CH2:34][CH:33]2[O:29][CH2:30][O:31][CH:32]2[CH2:36]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-06ba032fae214d029178f5f261eb0941
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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