Hydrochloric Acid → 7-Chloro-4-methoxy-1H-pyrrolo[2,3-c]pyridine

HRID 114618Notes

Reaction equation

HRID 114618 reaction equation
[Br:1][c:2]1[c:3]2[cH:4][cH:5][nH:6][c:7]2[c:8]([Cl:11])[n:9][cH:10]1.[CH3:12][O-:13].[CH3:16][OH:17].[ClH:15].[Cu:18][I:19].[Na+:14]>>[c:2]1([O:13][CH3:12])[c:3]2[cH:4][cH:5][nH:6][c:7]2[c:8]([Cl:11])[n:9][cH:10]1

Participants

7

Reactant 6

HCID 313Hydrochloric AcidHCID 887MethanolHCID 923Sodium ionHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 3826051MethoxideHCID 110317234-Bromo-7-chloro-1H-pyrrolo(2,3-c)pyridine

Product 1

HCID 159870137-Chloro-4-methoxy-1H-pyrrolo[2,3-c]pyridine

Sources & evidence

ORD record
ord-c1671ac1a6c34ecd93d51d241f0af584
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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