Acetic Acid → N-[dicyclopropyl-[5-[3-methyl-5-[[4-(trifluoromethyl)pyrimidin-2-yl]amino]phenyl]-1,3-thiazol-2-yl]methyl]-2-methylpropane-2-sulfinamide
Reaction equation
[CH3:46][C:47](=[O:48])[OH:49].[CH3:9][c:10]1[cH:11][c:12]([NH:21][c:22]2[n:23][cH:24][cH:25][c:26]([C:28]([F:29])([F:30])[F:31])[n:27]2)[cH:13][c:14](-[c:16]2[cH:17][n:18][cH:19][s:20]2)[cH:15]1.[CH:1]([N-:2][CH:3]([CH3:4])[CH3:5])([CH3:6])[CH3:7].[CH:32]1([C:35](=[N:36][S:37](=[O:38])[C:39]([CH3:40])([CH3:41])[CH3:42])[CH:43]2[CH2:44][CH2:45]2)[CH2:33][CH2:34]1.[Li+:8].[O:50]1[CH2:51][CH2:52][CH2:53][CH2:54]1>>[CH3:9][c:10]1[cH:11][c:12]([NH:21][c:22]2[n:23][cH:24][cH:25][c:26]([C:28]([F:29])([F:30])[F:31])[n:27]2)[cH:13][c:14](-[c:16]2[cH:17][n:18][c:19]([C:35]([CH:32]3[CH2:33][CH2:34]3)([NH:36][S:37](=[O:38])[C:39]([CH3:40])([CH3:41])[CH3:42])[CH:43]3[CH2:44][CH2:45]3)[s:20]2)[cH:15]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-1e42c6930aa64da792eb8575f7d5619d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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