Hydrochloric Acid → 4-(4-Chloro-2-fluorophenylamino)-7-hydroxy-6-methoxyquinazoline
Reaction equation
[CH2:2]([c:3]1[cH:4][cH:5][cH:6][cH:7][cH:8]1)[O:9][c:10]1[c:11]([O:29][CH3:30])[cH:12][c:13]2[c:14]([NH:20][c:21]3[c:22]([F:28])[cH:23][c:24]([Cl:27])[cH:25][cH:26]3)[n:15][cH:16][n:17][c:18]2[cH:19]1.[ClH:1].[F:31][C:32]([F:33])([F:34])[C:35]([OH:36])=[O:37]>>[OH:9][c:10]1[c:11]([O:29][CH3:30])[cH:12][c:13]2[c:14]([NH:20][c:21]3[c:22]([F:28])[cH:23][c:24]([Cl:27])[cH:25][cH:26]3)[n:15][cH:16][n:17][c:18]2[cH:19]1Participants
4
Sources & evidence
- ORD record
- ord-ed008d0b6197495fa073b5bec9842b56
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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