Acetate → 5-(4-Benzyloxyphenyl)-6-methyl-1-indanone

HRID 114747Notes

Reaction equation

HRID 114747 reaction equation
[C:63]([O-:64])(=[O:65])[CH3:66].[C:68]([O-:69])(=[O:70])[CH3:71].[CH2:20]([c:21]1[cH:22][cH:23][cH:24][cH:25][cH:26]1)[O:27][c:28]1[cH:29][cH:30][c:31]([B:34]([OH:35])[OH:36])[cH:32][cH:33]1.[CH:37]1([P:38]([CH:39]2[CH2:40][CH2:41][CH2:42][CH2:43][CH2:44]2)[CH:45]2[CH2:46][CH2:47][CH2:48][CH2:49][CH2:50]2)[CH2:51][CH2:52][CH2:53][CH2:54][CH2:55]1.[F-:56].[F:1][C:2]([F:3])([F:4])[S:5]([O:6][c:7]1[cH:8][c:9]2[c:13]([cH:14][c:15]1[CH3:16])[C:12](=[O:17])[CH2:11][CH2:10]2)(=[O:18])=[O:19].[K+:57].[O:58]1[CH2:59][CH2:60][CH2:61][CH2:62]1.[Pd+2:67]>>[c:7]1(-[c:31]2[cH:30][cH:29][c:28]([O:27][CH2:20][c:21]3[cH:22][cH:23][cH:24][cH:25][cH:26]3)[cH:33][cH:32]2)[cH:8][c:9]2[c:13]([cH:14][c:15]1[CH3:16])[C:12](=[O:17])[CH2:11][CH2:10]2

Participants

9

Reactant 8

HCID 175Acetate2×HCID 813Potassium CationHCID 8028TetrahydrofuranHCID 28179Fluoride IonHCID 75806TricyclohexylphosphineHCID 105144Allyl(1,3-bis(2,6-diisopropylphenyl)imidazol-2-ylidene)chloropalladium(II)HCID 27343144-Benzyloxy-phenylboronic acidHCID 211000385-(Trifluoromethanesulfonyloxy)-6-methyl-1-indanone

Product 1

HCID 211000315-(4-Benzyloxyphenyl)-6-methyl-1-indanone

Sources & evidence

ORD record
ord-7cf4a1caf9d543749390a1436fe88a4d
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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