Tetrahydrofuran → Ditert-butyl 4-oxopyrrolidine-1,2-dicarboxylate

HRID 1147711Notes

Reaction equation

HRID 1147711 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH:7]1[N:8]([C:13](=[O:14])[O:15][C:16]([CH3:17])([CH3:18])[CH3:19])[CH2:9][C:10](=[CH2:12])[CH2:11]1)=[O:20].[CH3:32][O:33][CH2:34][CH2:35][O:36][CH2:37][CH2:38][O:39][CH3:40].[CH:21]([BH:22][CH:23]([CH:24]([CH3:25])[CH3:26])[CH3:27])([CH:28]([CH3:29])[CH3:30])[CH3:31].[O:41]1[CH2:42][CH2:43][CH2:44][CH2:45]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6]([CH:7]1[N:8]([C:13](=[O:14])[O:15][C:16]([CH3:17])([CH3:18])[CH3:19])[CH2:9][C:10](=[O:33])[CH2:11]1)=[O:20]

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 8150DiglymeHCID 192733Bis(1,2-dimethylpropyl)boraneHCID 189679044-Methylene-pyrrolidine-1,2-dicarboxylic acid di-tert-butyl ester

Product 1

HCID 4110468Ditert-butyl 4-oxopyrrolidine-1,2-dicarboxylate

Sources & evidence

ORD record
ord-863d579fb74b422aa07ab7db7ca0b581
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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