Ammonium → Tert-butyl 3-[1-(1-benzothiophen-2-yl)-1-hydroxy-5-methoxypentyl]piperidine-1-carboxylate

HRID 1147799Notes

Reaction equation

HRID 1147799 reaction equation
[CH2:35]1[O:36][CH2:37][CH2:38][CH2:39]1.[CH3:26][O:27][CH2:28][CH2:29][CH2:30][CH2:31][Mg+:32].[Cl-:25].[Cl-:33].[NH4+:34].[s:1]1[c:2]2[c:3]([cH:4][c:5]1[C:6](=[O:7])[CH:8]1[CH2:9][N:10]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:11][CH2:12][CH2:13]1)[cH:21][cH:22][cH:23][cH:24]2>>[s:1]1[c:2]2[c:3]([cH:4][c:5]1[C:6]([OH:7])([CH:8]1[CH2:9][N:10]([C:14](=[O:15])[O:16][C:17]([CH3:18])([CH3:19])[CH3:20])[CH2:11][CH2:12][CH2:13]1)[CH2:31][CH2:30][CH2:29][CH2:28][O:27][CH3:26])[cH:21][cH:22][cH:23][cH:24]2

Participants

6

Reactant 5

HCID 223AmmoniumHCID 312Chloride2×HCID 8028TetrahydrofuranHCID 67190427Tert-butyl 3-(1-benzothiophene-2-carbonyl)piperidine-1-carboxylateHCID 178495007HCID 178495007, compound

Product 1

HCID 72282986Tert-butyl 3-[1-(1-benzothiophen-2-yl)-1-hydroxy-5-methoxypentyl]piperidine-1-carboxylate

Sources & evidence

ORD record
ord-b9f805989d6348de936c95150a46009f
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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