Chloride → 3-Bromo-7-[(2,4-dichloro-5-methoxyphenyl)amino]thieno[3,2-b]pyridine-6-carbonitrile

HRID 1148007Notes

Reaction equation

HRID 1148007 reaction equation
[Br:14][c:15]1[cH:16][s:17][c:18]2[c:19]1[n:20][cH:21][c:22]([C:25]#[N:26])[c:23]2[Cl:24].[Br:27][c:28]1[c:29]2[n:30][cH:31][c:32]([C:33]#[N:34])[c:35]([Br:36])[c:37]2[s:38][cH:39]1.[Cl-:41].[Cl:3][c:4]1[c:5]([NH2:6])[cH:7][c:8]([O:12][CH3:13])[c:9]([Cl:11])[cH:10]1.[H-:1].[Na+:2].[Na+:40].[O:42]1[CH2:43][CH2:44][CH2:45][CH2:46]1>>[Cl:3][c:4]1[c:5]([NH:6][c:23]2[c:18]3[s:17][cH:16][c:15]([Br:14])[c:19]3[n:20][cH:21][c:22]2[C:25]#[N:26])[cH:7][c:8]([O:12][CH3:13])[c:9]([Cl:11])[cH:10]1

Participants

8

Reactant 7

HCID 312ChlorideHCID 923Sodium ion2×HCID 8028TetrahydrofuranHCID 166653HydrideHCID 14766362,4-Dichloro-5-methoxyanilineHCID 112671073,7-Dibromothieno[3,2-b]pyridine-6-carbonitrileHCID 114146423-Bromo-7-chlorothieno[3,2-b]pyridine-6-carbonitrile

Product 1

HCID 113962683-Bromo-7-[(2,4-dichloro-5-methoxyphenyl)amino]thieno[3,2-b]pyridine-6-carbonitrile

Sources & evidence

ORD record
ord-bf88b7d313db48698a1a7018cb7785cf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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