Indole → 1-[4-(3-Pyrrolidin-1-ylpropoxy)phenyl]1H-indole

HRID 114851Notes

Reaction equation

HRID 114851 reaction equation
[Cu:40][I:41].[I:1][c:2]1[cH:3][cH:4][c:5]([O:6][CH2:7][CH2:8][CH2:9][N:10]2[CH2:11][CH2:12][CH2:13][CH2:14]2)[cH:15][cH:16]1.[NH2:26][CH:27]1[CH2:28][CH2:29][CH2:30][CH2:31][CH:32]1[NH2:33].[O:34]1[CH2:35][CH2:36][O:37][CH2:38][CH2:39]1.[nH:17]1[cH:18][cH:19][c:20]2[cH:21][cH:22][cH:23][cH:24][c:25]12>>[c:2]1(-[n:17]2[cH:18][cH:19][c:20]3[cH:21][cH:22][cH:23][cH:24][c:25]23)[cH:3][cH:4][c:5]([O:6][CH2:7][CH2:8][CH2:9][N:10]2[CH2:11][CH2:12][CH2:13][CH2:14]2)[cH:15][cH:16]1

Participants

6

Reactant 5

HCID 798IndoleHCID 46101,2-DiaminocyclohexaneHCID 24350Copper(1+) iodide; Copper(I) iodide; Cuprous iodide; Cuprous iodide (CuI)HCID 312751,4-DioxaneHCID 22325891-[3-(4-Iodophenoxy)propyl]pyrrolidine

Product 1

HCID 166619451-[4-(3-Pyrrolidin-1-ylpropoxy)phenyl]1H-indole

Sources & evidence

ORD record
ord-e9b2feff35e74068a23a4aad494d969e
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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