Hydrochloric Acid → (+/-)-1-[7-(2-Fluorophenyl)-2,3-dihydro-1-benzofuran-2-yl]methanamine

HRID 1148558Notes

Reaction equation

HRID 1148558 reaction equation
[CH3:1][c:2]1[cH:3][cH:4][c:5]([S:6]([O:7][CH2:8][CH:9]2[CH2:10][c:11]3[cH:12][cH:13][cH:14][c:15](-[c:16]4[cH:17][cH:18][cH:19][cH:20][c:21]4[F:22])[c:23]3[O:24]2)(=[O:25])=[O:26])[cH:27][cH:28]1.[ClH:56].[N-:30]=[N+:31]=[N-:32].[N-:53]=[N+:54]=[N-:55].[N:33](=[N+:34]=[N-:35])[CH2:36][CH:37]1[O:38][c:39]2[c:40]([cH:42][cH:43][cH:44][c:45]2-[c:46]2[c:47]([F:52])[cH:48][cH:49][cH:50][cH:51]2)[CH2:41]1.[Na+:29]>>[NH2:33][CH2:36][CH:37]1[O:38][c:39]2[c:40]([cH:42][cH:43][cH:44][c:45]2-[c:46]2[c:47]([F:52])[cH:48][cH:49][cH:50][cH:51]2)[CH2:41]1

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 923Sodium ionHCID 33558Azide2×HCID 86599085(+/-)-[7-(2-Fluorophenyl)-2,3-dihydro-1-benzofuran-2-yl]methyl 4-methylbenzenesulfonateHCID 86599200(+/-)-2-(Azidomethyl)-7-(2-fluorophenyl)-2,3-dihydro-1-benzofuran

Product 1

HCID 11960765(+/-)-1-[7-(2-Fluorophenyl)-2,3-dihydro-1-benzofuran-2-yl]methanamine

Sources & evidence

ORD record
ord-8271d2fcacdb40938905600cf0c720fe
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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