Dimethylformamide → tert-butyl N-[4-[3-[5-methoxy-3-(3-methoxypropyl)imidazo[4,5-b]pyridin-2-yl]piperidin-1-yl]-1-naphthalen-2-yl-4-oxobutan-2-yl]carbamate

HRID 1148797Notes

Reaction equation

HRID 1148797 reaction equation
[C:23]([CH3:24])([CH3:25])([CH3:26])[O:27][C:28](=[O:29])[NH:30][CH:31]([CH2:32][C:33](=[O:34])[OH:35])[CH2:36][c:37]1[cH:38][c:39]2[cH:40][cH:41][cH:42][cH:43][c:44]2[cH:45][cH:46]1.[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]2[c:7]([n:8]1)[n:9]([CH2:18][CH2:19][CH2:20][O:21][CH3:22])[c:10]([CH:12]1[CH2:13][NH:14][CH2:15][CH2:16][CH2:17]1)[n:11]2.[CH3:47][N:48]1[CH2:49][CH2:50][O:51][CH2:52][CH2:53]1.[O:78]=[CH:79][N:80]([CH3:81])[CH3:82].[P-:54]([F:55])([F:56])([F:57])([F:58])([F:59])[F:60].[n:61]1([O:62][C:63]([N:64]([CH3:65])[CH3:66])=[N+:67]([CH3:68])[CH3:69])[c:70]2[n:71][cH:72][cH:73][cH:74][c:75]2[n:76][n:77]1>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]2[c:7]([n:8]1)[n:9]([CH2:18][CH2:19][CH2:20][O:21][CH3:22])[c:10]([CH:12]1[CH2:13][N:14]([C:33]([CH2:32][CH:31]([NH:30][C:28]([O:27][C:23]([CH3:24])([CH3:25])[CH3:26])=[O:29])[CH2:36][c:37]3[cH:38][c:39]4[cH:40][cH:41][cH:42][cH:43][c:44]4[cH:45][cH:46]3)=[O:34])[CH2:15][CH2:16][CH2:17]1)[n:11]2

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 79724-MethylmorpholineHCID 9886HexafluorophosphateHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 533979213-(Boc-amino)-4-(2-naphthyl)butyric AcidHCID 667864945-Methoxy-3-(3-methoxypropyl)-2-(piperidin-3-yl)-3H-imidazo[4,5-b]pyridine

Product 1

HCID 66785171tert-butyl N-[4-[3-[5-methoxy-3-(3-methoxypropyl)imidazo[4,5-b]pyridin-2-yl]piperidin-1-yl]-1-naphthalen-2-yl-4-oxobutan-2-yl]carbamate

Sources & evidence

ORD record
ord-aca3e3ac47954de5803d0b7cc16d8897
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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