Hydrochloric Acid → Ethyl 7-(3-aminopyrrolidin-1-yl)-1-(2,4-difluorophenyl)-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylate
Reaction equation
[CH3:50][CH2:51][OH:52].[CH3:9][CH2:10][N:11]([CH2:12][CH3:13])[CH2:14][CH3:15].[ClH:1].[ClH:2].[NH2:3][CH:4]1[CH2:5][NH:6][CH2:7][CH2:8]1.[c:16]1([S:17](=[O:18])(=[O:19])[c:25]2[c:26]([F:49])[cH:27][c:28]3[c:29](=[O:48])[c:30]([C:43](=[O:44])[O:45][CH2:46][CH3:47])[cH:31][n:32](-[c:35]4[c:36]([F:42])[cH:37][c:38]([F:41])[cH:39][cH:40]4)[c:33]3[n:34]2)[cH:20][cH:21][cH:22][cH:23][cH:24]1>>[NH2:3][CH:4]1[CH2:5][N:6]([c:25]2[c:26]([F:49])[cH:27][c:28]3[c:29](=[O:48])[c:30]([C:43](=[O:44])[O:45][CH2:46][CH3:47])[cH:31][n:32](-[c:35]4[c:36]([F:42])[cH:37][c:38]([F:41])[cH:39][cH:40]4)[c:33]3[n:34]2)[CH2:7][CH2:8]1Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-64cd94f5abf640389418fa3a9aa90100
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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