Sodium ion → 3-[1-(2-Chlorophenyl)pyrazolo[5,4-d]pyrimidin-4-yl]oxypyrrolidin-2-one

HRID 1149834Notes

Reaction equation

HRID 1149834 reaction equation
[CH2:27]1[O:28][CH2:29][CH2:30][CH2:31]1.[Cl:10][c:11]1[c:12]2[c:13]([n:14][cH:15][n:16]1)[n:17](-[c:20]1[c:21]([Cl:26])[cH:22][cH:23][cH:24][cH:25]1)[n:18][cH:19]2.[H-:1].[Na+:2].[O:32]=[CH:33][N:34]([CH3:35])[CH3:36].[OH:3][CH:4]1[C:5](=[O:9])[NH:6][CH2:7][CH2:8]1>>[O:3]([CH:4]1[C:5](=[O:9])[NH:6][CH2:7][CH2:8]1)[c:11]1[c:12]2[c:13]([n:14][cH:15][n:16]1)[n:17](-[c:20]1[c:21]([Cl:26])[cH:22][cH:23][cH:24][cH:25]1)[n:18][cH:19]2

Participants

7

Reactant 6

HCID 923Sodium ionHCID 6228DimethylformamideHCID 8028TetrahydrofuranHCID 166653HydrideHCID 102407723-Hydroxy-2-pyrrolidinoneHCID 112655704-Chloro-1-(2-chlorophenyl)-1H-pyrazolo[3,4-D]pyrimidine

Product 1

HCID 765505283-[1-(2-Chlorophenyl)pyrazolo[5,4-d]pyrimidin-4-yl]oxypyrrolidin-2-one

Sources & evidence

ORD record
ord-def342b1b3764d73896a2ccee3be2215
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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