HRID1149925

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6228

Dimethylformamide

C3H7NO

HCID81531

Diisopropylethylamine

C8H19N

HCID53271816

2-Methyl-5-m-tolyl-thiazole-4-carboxylic acid

C12H11NO2S

反应SMILES：O=C1c2ccccc2C(=O)N1CC1NCC2CC(F)(F)CC21

HCID66703948

未命名化合物

PRODUCTS

产物

反应SMILES：Cc1cccc(-c2sc(C)nc2C(=O)N2CC3CC(F)(F)CC3C2CN2C(=O)c3ccccc3C2=O)c1

HCID66703706

未命名化合物

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-29338ad8b86f4942ad67a3ab3258071f
来源数据集: Training data from https://doi.org/10.1039/C8SC04228D (7/10)
DOI: 10.1039/C8SC04228D
来源说明: Training data from https://doi.org/10.1039/C8SC04228D (7/10)

反应SMILES

[CH3:1][c:2]1[s:3][c:4](-[c:10]2[cH:11][c:12]([CH3:16])[cH:13][cH:14][cH:15]2)[c:5]([C:7](=[O:8])[OH:9])[n:6]1.[CH:39]([N:40]([CH2:41][CH3:42])[CH:43]([CH3:44])[CH3:45])([CH3:46])[CH3:47].[F:17][C:18]1([F:38])[CH2:19][CH:20]2[CH2:21][NH:22][CH:23]([CH2:26][N:27]3[C:28](=[O:37])[c:29]4[cH:30][cH:31][cH:32][cH:33][c:34]4[C:35]3=[O:36])[CH:24]2[CH2:25]1.[O:48]=[CH:49][N:50]([CH3:51])[CH3:52]>>[CH3:1][c:2]1[s:3][c:4](-[c:10]2[cH:11][c:12]([CH3:16])[cH:13][cH:14][cH:15]2)[c:5]([C:7](=[O:9])[N:22]2[CH2:21][CH:20]3[CH2:19][C:18]([F:17])([F:38])[CH2:25][CH:24]3[CH:23]2[CH2:26][N:27]2[C:28](=[O:37])[c:29]3[cH:30][cH:31][cH:32][cH:33][c:34]3[C:35]2=[O:36])[n:6]1