1-Methylpyrrolidine → 1-(2-fluoro-4-(2-(1-methyl-1H-pyrazol-4-yl)pyridin-4-yloxy)phenyl)-3-(2-oxo-5-(trifluoromethyl)-1,2-dihydropyridin-3-yl)urea
Reaction equation
[CH2:46]1[O:47][CH2:48][CH2:49][O:50][CH2:51]1.[CH3:40][N:41]1[CH2:42][CH2:43][CH2:44][CH2:45]1.[CH3:52][CH2:53][O:54][C:55](=[O:56])[CH3:57].[F:13][c:14]1[c:15]([NH:33][C:34]([O:35][C:37]([CH3:38])=[CH2:39])=[O:36])[cH:16][cH:17][c:18]([O:20][c:21]2[cH:22][c:23](-[c:27]3[cH:28][n:29][n:30]([CH3:32])[cH:31]3)[n:24][cH:25][cH:26]2)[cH:19]1.[NH2:1][c:2]1[c:3](=[O:12])[nH:4][cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1>>[NH:1]([c:2]1[c:3](=[O:12])[nH:4][cH:5][c:6]([C:8]([F:9])([F:10])[F:11])[cH:7]1)[C:34]([NH:33][c:15]1[c:14]([F:13])[cH:19][c:18]([O:20][c:21]2[cH:22][c:23](-[c:27]3[cH:28][n:29][n:30]([CH3:32])[cH:31]3)[n:24][cH:25][cH:26]2)[cH:17][cH:16]1)=[O:35]Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-963873059ec54f769e9db921b54f8c63
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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