N-methyl-2-pyrrolidone → 2-[2-(2,4-Difluoro-phenyl)-2H-[1,2,4]triazol-3-yl]-9-(6-pyrrolidin-1-yl-pyridin-3-yl)-4,5-dihydro-6-oxa-1-thia-10-aza-benzo[e]azulene
Reaction equation
[CH2:35]1[CH2:36][CH2:37][NH:38][CH2:39]1.[CH3:40][N:41]1[CH2:42][CH2:43][CH2:44][C:45]1=[O:46].[F:1][c:2]1[c:3](-[n:9]2[n:10][cH:11][n:12][c:13]2-[c:14]2[cH:15][c:16]3[c:22]([s:23]2)-[c:21]2[c:20]([cH:27][cH:26][c:25](-[c:28]4[cH:29][n:30][c:31]([F:34])[cH:32][cH:33]4)[n:24]2)[O:19][CH2:18][CH2:17]3)[cH:4][cH:5][c:6]([F:8])[cH:7]1>>[F:1][c:2]1[c:3](-[n:9]2[n:10][cH:11][n:12][c:13]2-[c:14]2[cH:15][c:16]3[c:22]([s:23]2)-[c:21]2[c:20]([cH:27][cH:26][c:25](-[c:28]4[cH:29][n:30][c:31]([N:38]5[CH2:37][CH2:36][CH2:35][CH2:39]5)[cH:32][cH:33]4)[n:24]2)[O:19][CH2:18][CH2:17]3)[cH:4][cH:5][c:6]([F:8])[cH:7]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-ce48b45c374a4cc4a435203e6f4d7f8d
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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