Sodium ion → 3-Chloro-5-fluoro[1,1′-biphenyl]-4-amine

HRID 1151756Notes

Reaction equation

HRID 1151756 reaction equation
[F:1][c:2]1[c:3]([NH2:4])[c:5]([Cl:10])[cH:6][c:7]([I:9])[cH:8]1.[Na+:20].[Na+:21].[O-:22][C:23](=[O:24])[O-:25].[O:26]=[CH:27][N:28]([CH3:29])[CH3:30].[OH:11][B:12]([OH:13])[c:14]1[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[F:1][c:2]1[c:3]([NH2:4])[c:5]([Cl:10])[cH:6][c:7](-[c:14]2[cH:15][cH:16][cH:17][cH:18][cH:19]2)[cH:8]1

Participants

6

Reactant 5

HCID 923Sodium ion2×HCID 6228DimethylformamideHCID 19660Carbonate IonHCID 66827Phenylboronic AcidHCID 18451511HCID 18451511, compound

Product 1

HCID 184515133-Chloro-5-fluoro[1,1′-biphenyl]-4-amine

Sources & evidence

ORD record
ord-3cb49ee848164085bed32b680d62335c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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