Methanol → tert-butyl 3-(fluoromethyl)-3-[4-(7-{[2-(trimethylsilyl)ethoxy]methyl}-7H-pyrrolo[2,3-d]pyrimidin-4-yl)-1H-pyrazol-1-yl]azetidine-1-carboxylate
Reaction equation
[CH3:52][OH:53].[CH3:54][CH2:55][O:56][C:57]([CH3:58])=[O:59].[F:1][CH:2]([C:3]1([n:14]2[n:15][cH:16][c:17](-[c:19]3[c:20]4[c:21]([n:22][cH:23][n:24]3)[n:25]([CH2:28][O:29][CH2:30][CH2:31][Si:32]([CH3:33])([CH3:34])[CH3:35])[cH:26][cH:27]4)[cH:18]2)[CH2:4][N:5]([C:7](=[O:8])[O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[CH2:6]1)[S:36]([c:37]1[cH:38][cH:39][cH:40][cH:41][cH:42]1)(=[O:43])=[O:44].[Hg:60].[Na+:50].[Na+:51].[Na:61].[P:45]([O-:46])([O-:47])([OH:48])=[O:49]>>[F:1][CH2:2][C:3]1([n:14]2[n:15][cH:16][c:17](-[c:19]3[c:20]4[c:21]([n:22][cH:23][n:24]3)[n:25]([CH2:28][O:29][CH2:30][CH2:31][Si:32]([CH3:33])([CH3:34])[CH3:35])[cH:26][cH:27]4)[cH:18]2)[CH2:4][N:5]([C:7](=[O:8])[O:9][C:10]([CH3:11])([CH3:12])[CH3:13])[CH2:6]1Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-9791f79e37c045abb5fb64cf0f804ffa
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
Loading…