Tetrahydrofuran → Benzyl 5-((4-(hydroxymethyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)methyl)-2,3-dihydro-1H-inden-1-ylcarbamate
Reaction equation
[Al+3:37].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[NH:11][CH:12]1[CH2:13][CH2:14][c:15]2[cH:16][c:17]([CH2:21][n:22]3[n:23][c:24]([C:32]([F:33])([F:34])[F:35])[c:25]([C:27](=[O:28])[O:29][CH2:30][CH3:31])[cH:26]3)[cH:18][cH:19][c:20]21.[CH2:42]1[O:43][CH2:44][CH2:45][CH2:46]1.[H-:36].[H-:39].[H-:40].[H-:41].[Li+:38]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[O:8][C:9](=[O:10])[NH:11][CH:12]1[CH2:13][CH2:14][c:15]2[cH:16][c:17]([CH2:21][n:22]3[n:23][c:24]([C:32]([F:33])([F:34])[F:35])[c:25]([CH2:27][OH:28])[cH:26]3)[cH:18][cH:19][c:20]21Participants
6
Reactant 5
Product 1
Sources & evidence
- ORD record
- ord-59ae209f5635411ab6e1e251885d219c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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