4-Methylmorpholine → LCZ696 InteMediate

HRID 1152185Notes

Reaction equation

HRID 1152185 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH:9]([C:10](=[O:11])[OH:12])[CH2:13][c:14]1[cH:15][cH:16][c:17](-[c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[cH:18][cH:19]1.[CH2:41]([CH2:42][O:43][CH3:44])[O:45][CH3:46].[CH3:26][N:27]1[CH2:28][CH2:29][O:30][CH2:31][CH2:32]1.[Cl:33][C:34]([O:35][CH2:36][CH:37]([CH3:38])[CH3:39])=[O:40]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[NH:8][CH:9]([CH2:10][OH:11])[CH2:13][c:14]1[cH:15][cH:16][c:17](-[c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)[cH:18][cH:19]1

Participants

5

Reactant 4

HCID 79724-MethylmorpholineHCID 80711,2-DimethoxyethaneHCID 62365Isobutyl chloroformateHCID 46239082-[(2-methylpropan-2-yl)oxycarbonylamino]-3-(4-phenylphenyl)propanoic Acid

Product 1

HCID 19427706LCZ696 InteMediate

Sources & evidence

ORD record
ord-d0bfb0fa228e4fa79b70ae3e05ff4acf
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

Loading…