Diethyl Ether → Tert-butyl 3-(4-{({4'-[2-(ethylthio)ethoxy]-2',6'-dimethylbiphenyl-3-yl}methyl)[(2-nitrophenyl)sulfonyl]amino}-2-fluorophenyl)propanoate
Reaction equation
[CH2:46]([CH3:47])[S:48][CH2:49][CH2:50][OH:51].[CH2:52]([P:53]([CH2:54][CH2:55][CH2:56][CH3:57])[CH2:58][CH2:59][CH2:60][CH3:61])[CH2:62][CH2:63][CH3:64].[CH3:88][CH2:89][O:90][CH2:91][CH3:92].[F:1][c:2]1[c:3]([CH2:37][CH2:38][C:39](=[O:40])[O:41][C:42]([CH3:43])([CH3:44])[CH3:45])[cH:4][cH:5][c:6]([N:8]([S:9](=[O:10])(=[O:11])[c:12]2[c:13]([N+:18](=[O:19])[O-:20])[cH:14][cH:15][cH:16][cH:17]2)[CH2:21][c:22]2[cH:23][c:24](-[c:28]3[c:29]([CH3:36])[cH:30][c:31]([OH:35])[cH:32][c:33]3[CH3:34])[cH:25][cH:26][cH:27]2)[cH:7]1.[N:65]([C:66]([N:67]1[CH2:68][CH2:69][CH2:70][CH2:71][CH2:72]1)=[O:73])=[N:74][C:75]([N:76]1[CH2:77][CH2:78][CH2:79][CH2:80][CH2:81]1)=[O:82].[O:83]1[CH2:84][CH2:85][CH2:86][CH2:87]1>>[F:1][c:2]1[c:3]([CH2:37][CH2:38][C:39](=[O:40])[O:41][C:42]([CH3:43])([CH3:44])[CH3:45])[cH:4][cH:5][c:6]([N:8]([S:9](=[O:10])(=[O:11])[c:12]2[c:13]([N+:18](=[O:19])[O-:20])[cH:14][cH:15][cH:16][cH:17]2)[CH2:21][c:22]2[cH:23][c:24](-[c:28]3[c:29]([CH3:36])[cH:30][c:31]([O:35][CH2:50][CH2:49][S:48][CH2:46][CH3:47])[cH:32][c:33]3[CH3:34])[cH:25][cH:26][cH:27]2)[cH:7]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-9a4b0c42ecb5422e8366060a08add335
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (7/10)
Reaction notes
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