Tetrahydrofuran → 3-(4'-Bromo-biphenyl-4-yloxymethyl)-2-methoxy-pyridine

HRID 1152496Notes

Reaction equation

HRID 1152496 reaction equation
[Br:44][c:45]1[cH:46][cH:47][c:48](-[c:51]2[cH:52][cH:53][c:54]([OH:57])[cH:55][cH:56]2)[cH:49][cH:50]1.[CH2:58]1[O:59][CH2:60][CH2:61][CH2:62]1.[CH3:34][O:35][c:36]1[n:37][cH:38][cH:39][cH:40][c:41]1[CH2:42][OH:43].[O:20]=[C:21]([O:22][CH:23]([CH3:24])[CH3:25])[N:26]=[N:27][C:28]([O:29][CH:30]([CH3:31])[CH3:32])=[O:33].[c:1]1([P:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[CH3:34][O:35][c:36]1[n:37][cH:38][cH:39][cH:40][c:41]1[CH2:42][O:43][c:54]1[cH:53][cH:52][c:51](-[c:48]2[cH:47][cH:46][c:45]([Br:44])[cH:50][cH:49]2)[cH:56][cH:55]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 11776TriphenylphosphineHCID 75555Diisopropyl diazene-1,2-dicarboxylateHCID 950934-Bromo-4'-hydroxybiphenylHCID 10630565(2-Methoxypyridin-3-yl)methanol

Product 1

HCID 685127243-(4'-Bromo-biphenyl-4-yloxymethyl)-2-methoxy-pyridine

Sources & evidence

ORD record
ord-095286a29b3f480cbd8048df40485ab3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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