Potassium Cation → [5-(1-Butyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine

HRID 1152654Notes

Reaction equation

HRID 1152654 reaction equation
[Br:36][CH2:37][CH2:38][CH2:39][CH3:40].[C:30](=[O:31])([O-:32])[O-:33].[CH3:41][C:42]([N:43]([CH3:44])[CH3:45])=[O:46].[K+:34].[K+:35].[nH:1]1[n:2][cH:3][c:4](-[c:6]2[cH:7][cH:8][cH:9][c:10]3[n:11]2[n:12][c:13]([NH:15][c:16]2[cH:17][cH:18][c:19]([O:22][CH2:23][CH2:24][N:25]4[CH2:26][CH2:27][CH2:28][CH2:29]4)[cH:20][cH:21]2)[n:14]3)[cH:5]1>>[n:1]1[n:2]([CH2:37][CH2:38][CH2:39][CH3:40])[cH:3][c:4](-[c:6]2[cH:7][cH:8][cH:9][c:10]3[n:11]2[n:12][c:13]([NH:15][c:16]2[cH:17][cH:18][c:19]([O:22][CH2:23][CH2:24][N:25]4[CH2:26][CH2:27][CH2:28][CH2:29]4)[cH:20][cH:21]2)[n:14]3)[cH:5]1

Participants

6

Reactant 5

HCID 813Potassium Cation2×HCID 8002Butyl bromideHCID 19660Carbonate IonHCID 31374DimethylacetamideHCID 136146545[5-(1H-Pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine

Product 1

HCID 59589548[5-(1-Butyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[1,5-a]pyridin-2-yl]-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine

Sources & evidence

ORD record
ord-a72f9edbac60455db1660a6422dc1491
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (7/10)

Reaction notes

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