Hydrochloric Acid → 6-Methoxy-7-((1-(2-methylsulphonylethyl)piperidin-4-yl)methoxy)-3-((pivaloyloxy)methyl)-3,4-dihydroquinazolin-4-one
Reaction equation
[C:1](=[O:2])([O-:3])[O-:4].[CH2:52]([Cl:53])[Cl:54].[CH3:14][O:15][c:16]1[cH:17][c:18]2[c:19](=[O:42])[n:20]([CH2:34][O:35][C:36]([C:37]([CH3:38])([CH3:39])[CH3:40])=[O:41])[cH:21][n:22][c:23]2[cH:24][c:25]1[O:26][CH2:27][CH:28]1[CH2:29][CH2:30][NH:31][CH2:32][CH2:33]1.[CH3:43][CH2:44][N:45]([CH2:46][CH3:47])[CH2:48][CH3:49].[CH3:50][OH:51].[CH:7](=[CH2:8])[S:9](=[O:10])(=[O:11])[CH3:12].[ClH:13].[K+:5].[K+:6]>>[CH2:7]([CH2:8][N:31]1[CH2:30][CH2:29][CH:28]([CH2:27][O:26][c:25]2[c:16]([O:15][CH3:14])[cH:17][c:18]3[c:19](=[O:42])[n:20]([CH2:34][O:35][C:36]([C:37]([CH3:38])([CH3:39])[CH3:40])=[O:41])[cH:21][n:22][c:23]3[cH:24]2)[CH2:33][CH2:32]1)[S:9](=[O:10])(=[O:11])[CH3:12]Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-76e00b35732542f6b949c2ce36b6b024
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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