Hydrochloric Acid → HCID 135759124, compound

HRID 1153853Notes

Reaction equation

HRID 1153853 reaction equation
[NH2:1][C:2]1[CH:16]=[C:15]([N+:17]([O-:19])=[O:18])[CH:14]=[CH:13][C:3]=1[NH:4][C:5]1[C:9]([C:10]#[N:11])=[CH:8][N:7]([CH3:12])[N:6]=1.[ClH:20]>C(O)(C)C>[ClH:20].[NH2:11][C:10]1[C:9]2[C:5](=[N:6][N:7]([CH3:12])[CH:8]=2)[NH:4][C:3]2[CH:13]=[CH:14][C:15]([N+:17]([O-:19])=[O:18])=[CH:16][C:2]=2[N:1]=1

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 12888760HCID 12888760, compound

Product 1

HCID 135759124HCID 135759124, compound

Reagents, catalysts & solvents 1

HCID 3776IsopropanolSolvent

Procedure

3-(2-Amino-4-nitroanilino)-1-methylpyrazole-4-carbonitrile (250 mg) was heated under reflux in a mixture of isopropanol (10 ml) and concentrated hydrochloric acid (1 ml) for 20 hours. The solution was evaporated under reduced pressure and the residue crystallised from methylated spirits to give the title compound m.p. >260°.

Workup

  1. customThe solution was evaporated under reduced pressure
  2. customthe residue crystallised from methylated spirits

Sources & evidence

ORD record
ord-26792b2471d74b51ace2a3f90254640c
Source dataset
uspto-grants-1984_12
Patent number
US04486591

Reaction notes

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