Methylamine → HCID 70505503, compound

HRID 1154700Notes

Reaction equation

HRID 1154700 reaction equation
[CH3:1][N:2]([CH2:4][C:5]1[N:10]=[C:9]([S:11][CH2:12][CH2:13][CH2:14][NH:15][C:16](SC)=[CH:17][N+:18]([O-:20])=[O:19])[CH:8]=[CH:7][CH:6]=1)[CH3:3].[CH3:23][NH2:24]>C(O)C>[CH3:1][N:2]([CH2:4][C:5]1[N:10]=[C:9]([S:11][CH2:12][CH2:13][CH2:14][NH:15][C:16]([NH:24][CH3:23])=[CH:17][N+:18]([O-:20])=[O:19])[CH:8]=[CH:7][CH:6]=1)[CH3:3]

Participants

4

Reactant 2

HCID 6329MethylamineHCID 70506038HCID 70506038, compound

Product 1

HCID 70505503HCID 70505503, compound

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

1-[3-(6-Dimethylaminomethyl-2-pyridylthio) propylamino]-1-methylthio-2-nitroethene (1.25 g, 0.0037 mol) is added to ethanol (15 ml) saturated with monomethylamine gas at ice bath temperature and is allowed to stir at ambient temperature for 18 hours. The reaction solvent is removed and the residue is chromatographed on silica gel (50 g) eluting with 5-20% methanol/chloroform to 1.1 g of a glassy product.

Workup

  1. customThe reaction solvent is removed
  2. customthe residue is chromatographed on silica gel (50 g)
  3. washeluting with 5-20% methanol/chloroform to 1.1 g of a glassy product

Sources & evidence

ORD record
ord-179e5c626f494075aa8b1cb396145d9e
Source dataset
uspto-grants-1984_12
Patent number
US04490533

Reaction notes

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