4-Hydroxybenzaldehyde → 3-[4-(1-Piperidinylmethyl)phenoxy]-1-propanamine

HRID 1154723Notes

Reaction equation

[NH:1]1[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[OH:7][C:8]1[CH:15]=[CH:14][C:11]([CH:12]=O)=[CH:10][CH:9]=1>>[N:1]1([CH2:12][C:11]2[CH:14]=[CH:15][C:8]([O:7][CH2:4][CH2:3][CH2:2][NH2:1])=[CH:9][CH:10]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

Participants

Reactant 2

HCID 1264-Hydroxybenzaldehyde

HCID 8082Piperidine

Product 1

HCID 140865533-[4-(1-Piperidinylmethyl)phenoxy]-1-propanamine

Procedure

Starting materials:piperidine and 4-hydroxybenzaldehyde

Sources & evidence

ORD record: ord-0da0313f45da4b959da053e4019edddb
Source dataset: uspto-grants-1984_12
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04490527

Reaction notes

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